Cisplatin for horses

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WebSep 1, 2024 · Cisplatin for injection has been administered at 50 mg/m 2 to 70 mg/m 2 intravenously per cycle once every 3 to 4 weeks. For heavily pretreated patients, an … WebDec 29, 2000 · Cisplatin is a heavy metal compound that stops cell division and causes cell death. It has been used by intratumoral (into the tumor) injection in the treatment of sarcoids with an 87% success...

Cisplatin beads Medication & Information for Animals

http://royerbiomedical.com/products-in-development/ WebTable 1. Local Control Rates in 378 Horses With 409 Sarcoids Treated By Intratumoral Chemotherapy With Cisplatin Alone or in Combination With Surgery Treatment … photo gaspillage

Intratumoral Administration of Cisplatin for Treatment of

WebNov 6, 2013 · Melanin is a pigment produced by melanocytes in the basal layer of the epidermis. It is proposed that, in grey horses, a disturbance in melanin metabolism and transfer associated with progressive greying of the hair, due to increasing age, results in intra-cellular accumulation of pigment. WebNov 15, 2006 · Abstract Objective—To determine outcome for equids with cutaneous neoplasms treated with cisplatin-containing biodegradable beads, alone or in conjunction with debulking. Design—Retrospective case series. Animals—56 horses, 1 zebra, 1 donkey, and 1 mule. Procedures—Medical records were reviewed. Follow-up information … WebDec 1, 2006 · For the administration route of these two chemotherapeutic drugs, cisplatin was mainly administered intratumorally in the form of the biodegradable bead (placed at 1.5 or 2 cm intervals depending... photo gastlosen

Review of the Treatment of Equine Cutaneous Neoplasia - AAEP

Equine Sarcoids - Integumentary System - Merck Veterinary Manual

WebIntratumoral Administration of Cisplatin for Treatment of Sarcoids in 378 Horses AAEP. Home. >. Intratumoral Administration of Cisplatin for Treatment of Sarcoids in 378 … WebDec 4, 2012 · Bovine papillomavirus type 1 infects not only cattle but also equids and is a causative factor in the pathogenesis of commonly occurring equine sarcoid tumours. Whilst treatment of sarcoids is notoriously difficult, cisplatin has been shown to be one of the most effective treatment strategies for sarcoids. In this study we show that in equine … how does geothermal energy create energyWebNov 15, 2006 · Objective: To determine outcome for equids with cutaneous neoplasms treated with cisplatin-containing biodegradable beads, alone or in conjunction with debulking. Design: Retrospective case series. Animals: 56 horses, 1 zebra, 1 donkey, and 1 mule. Procedures: Medical records were reviewed. Follow-up information was obtained … photo garter snake

"WebMay 15, 2024 · Intralesional injection with cisplatin has been reported to be effective in some cases. In the 1980s. the antihistamine, cimetidine, was reported as causing tumor remission in a small group of horses; … " - Cisplatin for horses

Cisplatin for horses

Cisplatin for Sarcoids, Carcinomas – The Horse

WebJan 25, 2024 · treatment as needed to minimize inﬂammation at the site of injection. Fourteen horses had a treat- ment session delayed for 1 wk between the third and fourth administration because of acute skin reaction (grade 3). The risk of developing a grade 3 skin reaction was higher in horses treated previously with cryotherapy (p 0.02) or use of … WebCisplatin (cisplatinum or cis-diamminedichloroplatinum(i)) is a platinum-based chemotherapy drug used to treat various types of skin cancers of horses, …

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WebIntratumoral chemotherapy with cisplatin is a practical, effective, and inexpensive method of treatment for equine sarcoids. Treatment resulted in no cosmetic or functional deficits. Factors that negatively affected treatment efficacy included larger tumor size and prior use of other treatment modalities. WebCisplatin has shown activity against osteosarcoma, transitional cell carcinoma, squamous cell carcinoma (SCC), melanoma, mesothelioma, carcinomatosis and germinal cell tumours in the dog. In the cat, cisplatin cannot be utilized because of fulminant pulmonary oedema that occurs at standard doses.

WebConclusions: Cisplatin and bleomycin were effective anticancer agents for carcinoma of the eyelid in horses. Based on therapeutic benefit and treatment cost, cisplatin was found to be a better choice for intratumoral chemotherapy of eyelid carcinomas. WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. …

WebA variety of chemotherapy drugs are available for use in horses. Cisplatin in one of the most effective and commonly used in horses, … WebJan 1, 2000 · Horses were given 4 intratumoral treatments of cisplatin at 2-week intervals. The first treatment was given at the time of, or immediately after, surgical resection for horses treated in ...

WebDec 1, 1999 · Objective: To determine the benefits of reducing the interval between surgical cytoreduction and intratumoral administration of cisplatin. Design: Randomized clinical study. Animals: 70 horses with 89 incompletely resected T2- and T3-stage sarcoids (n = 64) and squamous cell carcinomas (25). Procedure: Horses were given 4 intratumoral …

WebApr 3, 2024 · In this study 25 horses diagnosed with canker also tested positive for bovine papillomavirus DNA, which can lead to sarcoid development. Based on these results, … how does geothermal generate electricityWebSep 26, 2012 · Intratumoural cisplatin, 5-fluorouracil (5-FU), mitomycin-C and bleomycin have been used to treat equine MC-SCC. Cisplatin (cis-diammine dichloroplatinum) … photo gartic phoneWebMelanomas may be single or multiple. Treatment is cimetidine, surgical excision and/or cryotherapy. Sarcoids are solitary or multiple tumors of the eyelids and periocular region … how does geothermal power plant worksWebDec 5, 2007 · Cisplatin (cis-diamminedichloroplatinum) is commonly used as an intralesional chemotherapeutic agent for equine cutaneous tumors and has been found to be effective against a variety of solid tumors [5 … photo gaspard ullielWebProduct Description: Cisplatin Resorbable Sustained Release Implant is comprised of a proprietary combination of Calcium Sulfate Hemihydrate USP, Dextran Sulfate Sodium Salt and Cisplatin USP. Each ~3mm bead contains 1.6mg of Cisplatin that is slowly released at the site of implantation over a period of 7-10 days. photo gastroWebJan 25, 2024 · horses. Prognostic factors signiﬁcantly affecting local control were tumor size before cisplatin treat-ment and previous unsuccessful treatment. Large tumors and … how does geothermal plant worksWebApr 24, 2008 · Placing bioabsorbable beads of the chemotherapeutic agent cisplatin in a tumor allows for a slow release of chemotherapy. The beads are 3 mm wide and contain … photo gaston