Plekhm2 salmonella

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August undefined, 2024

WebDec 20, 2015 · The PLEKHM2 cDNA2156_2157delAG variant causes the frameshift p.Lys645AlafsTer12 and/or the skipping of exon 11 that results in deletion of 30 highly … WebDec 11, 2014 · The host endolysosomal compartment is often manipulated by intracellular bacterial pathogens. Salmonella (Salmonella enterica serovar Typhimurium) secrete numerous effector proteins, including SifA, through a specialized type III secretion system to hijack the host endosomal system and generate the Salmonella-containing vacuole …

Anti-PLEKHM2 Antibodies Invitrogen - Thermo Fisher Scientific

WebSalmonella infection (salmonellosis) is a bowel infection caused by salmonella bacteria. It usually gets better by itself within a week, but some people need to take antibiotics. Some people can become very unwell with dehydration. You can catch salmonella from eating infected animal products or from contact with animals or sick people. WebNov 13, 2007 · Salmonella-induced filaments A and kinesin-interacting protein 1 publication (SifA and kinesin-interacting protein 1 publication) Gene names. Name. ... Interacts (via … batirad

Salmonella: Outbreaks, Causes, Symptoms & Treatment - Cleveland Clinic

http://genome.cse.ucsc.edu/cgi-bin/hgGene?org=Human&hgg_chrom=none&hgg_type=knownGene&hgg_gene=uc010obo.2 WebDec 1, 2016 · Another Salmonella effector, SifA, engages SKIP and kinesin-1 to pinch off vesicles from the Salmonella vacuole and move them in anterograde direction (Dumont et al., 2010). SifA also forms a complex with SKIP and Rab9A, preventing transport of mannose 6-phosphate receptors (MPRs) from endosomes to the TGN and thus causing … • Boucrot E, Henry T, Borg JP, Gorvel JP, Méresse S (May 2005). "The intracellular fate of Salmonella depends on the recruitment of kinesin". Science. 308 (5725): 1174–8. Bibcode:2005Sci...308.1174B. doi:10.1126/science.1110225. PMID 15905402. S2CID 41055820. • Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. XII. The … bati rack legrand

Pharos : Target Details - PLEKHM2 - National Institutes of Health

PLEKHM2 Gene - GeneCards PKHM2 Protein PKHM2 Antibody

WebSalmonella enterica is an intracellular bacterial pathogen that replicates within membrane-bound vacuoles through the action of effector proteins translocated into host cells. ... This required binding of SifA to its host cell target SKIP/PLEKHM2. WebDownload scientific diagram Kxd1 and Plekhm2 required for evasion of starvation-induced autophagic elimination by the BJN strain. (a) Raw264.7 cells were transfected with non … tenuta ponziani bookingWebCDC estimates Salmonella bacteria cause about 1.35 million infections, 26,500 hospitalizations, and 420 deaths in the United States every year. Food is the source for most of these illnesses. Most people who get ill from Salmonella have diarrhea, fever, and stomach cramps. batir a banger

"WebOther studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo. IgGy Antibody Selector – Quickly search hundreds of thousands of antibodies available for purchase from VWR by selecting … " - Plekhm2 salmonella

Plekhm2 salmonella

PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING PROTEIN, …

WebSalmonella infection: Abnormal: Citrobacter infection: Normal: All tests and analysis from: Model organisms have been used in the study of PLEKHM2 function. A conditional knockout mouse line, called Plekhm2 tm1a(EUCOMM)Wtsi was ... WebPLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in …

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WebNov 16, 2012 · Salmonella vacuoles have characteristics of lysosomes but are reduced in hydrolytic enzymes transported by mannose-6-phosphate receptors (MPRs). We found … WebOther studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo. Application Note. Anti-PLEKHM2 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and ...

WebThe PLEKHM2-IGF2BP2 Fusion FISH Probe is used to confirm a fusion of the PLEKHM2 and IGF2BP2 genes. The fusion of the PLEKHM2 and IGF2BP2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround … WebPLEKHM2 (KIAA0842) protein expression summary. We use cookies to enhance the usability of our website. ... It binds a Salmonella effector protein called Salmonella …

WebJul 13, 2024 · Introduction. The food-borne, facultative intracellular pathogen Salmonella enterica serovar Typhimurium (STM) is the etiological agent of gastroenteritis in humans or systemic infections in mice [].An early step in disease is the active invasion of epithelial cells. This process is dependent on the translocation of effector proteins by STM into the host … WebIt binds a Salmonella effector protein called Salmonella induced filament A and is a critical host determinant in Salmonella pathogenesis. It has a domain architecture consisting of an N-terminal RPIP8, UNC-14, and NESCA (RUN) domain that binds kinesin-1 as well as the lysosomal GTPase Arl8, and a C-terminal pleckstrin homology domain that binds the …

WebIt binds a Salmonella effector protein called Salmonella induced filament A and is a critical host determinant in Salmonella pathogenesis. It has a domain architecture consisting of an N-terminal RPIP8, UNC-14, and NESCA (RUN) domain that binds kinesin-1 as well as the lysosomal GTPase Arl8, and a C-terminal pleckstrin homology domain that binds the …

WebThe Salmonella SPI-2 type III secretion system transfers a large number of effector proteins to host cells. In this Review, Holden and colleagues summarize the biochemical activities, host cell interaction partners, and physiological functions of these effectors in the context of the selective pressures encountered by S. enterica in vivo. batiqa hotel lampungWebDec 10, 2014 · To form this replicative niche, Salmonella targets the Rab7 GTPase to recruit host membranes through largely unknown mechanisms. We show that Pleckstrin homology domain-containing protein family ... tenuta naplesWebInvitrogen Anti-PLEKHM2 Polyclonal, Catalog # PA5-20850. Tested in Western Blot (WB) and Immunohistochemistry (IHC) applications. This antibody ... Other studies have … bati racanWebPLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining … batiqa hotel \u0026 apartments karawangWebMar 21, 2024 · PLEKHM1 and PLEKHM2 compete for interaction with ARL8B (PubMed:28325809). ... In case of infection contributes to Salmonella typhimurium pathogenesis by supporting the integrity of the Salmonella-containing vacuole (SCV) probably in concert with the HOPS complex and Rab7. tenuta\u0027sWebTarget Information. PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a … tenuta maraveja brendolahttp://conditions.health.qld.gov.au/HealthCondition/condition/14/33/124/Salmonella-infection-salmonellosis batiqa hotel palembang